Pay by echeck & get $10 medicine free

Toll Free Tel +1 (888) 609 2505 Mon-Fri 06.00 AM - 10.00 PM (PST)


BRIMONIDINE (bri-MOE-ni-deen)+TIMOLOL (TIM-oh-lole)

Be the first to review this product

Availability: In stock



Quantity Stength Unit Price Price Cart
1 Bottle Combigan Solution 0.2-0.5 5ml Bottle $31.99 $31.99
3 Bottle Combigan Solution 0.2-0.5 5ml Bottle $31.33 $93.99

* Required Fields



Combigan combined formulation is used for  effective treatment of open angle glaucoma and ocular hypertension. It contains Brimonidine 0.2% and Timolol 0.5% belonging to Alpha adrenergic agonist and beta adrenergic blocker respectively. Combigan is an US FDA approved drug. This acts on aqueous humor and decrease the inner pressure of eye. Increase in IOP is a reason for blindness. Combigan can be instilled thrice a day one drop each medication.

The drug acts by decreasing the intra ocular pressure by decreasing the production of aqueous humor which increases the pressure inside the eyes. The drug also increases the out flow of liquid out of aqueous humor this over all decreases the pressure inside the eye.


  • Patient Hypersensitive to ingredient
  • Neonate and infants below age of 2year should remain refrained from drug.
  • Sinus Bradycardia and COPD and bronchial asthma patient should not take the medicament.

Drug interaction with

  • Antihypertensive drugs cardiac glycosides may cause severe side effect and bring hypotension to the patient.
  • Digitalis and calcium agonist should not be taken along Combigan eye drop.
  • Mono oxidase inhibitors should be avoided along the medicine.
  • Tricyclic antidepressants increases the side effect and drowsiness of the drug
  • Oral beta blockers may bring hypotension.

Storage conditions for Combigan eye drop: one should keep the medicine out of reach of children. Keep it in cool and shady place. Put the cap tightly closed after using the eye drop. Once eye drop is opened one should use it in 15 days.

Dose and dossier:

One should put one drop for three times in a day. One should instill the eye drop to the effected eyes after 8-12 hour of gap. One should put the eye drop while tilting head back. Instill the eye drop wide open by pulling the lower eye lid downward.

If one is on different ophthalmic medication he/ she should take the medication after 10 minutes gap and if you are taking eye ointment then keep eye drop first at priority and later you can use the eye ointment.

One should not touch the tip of eye drop as it may compromise the sterility of the drug. One must replace the cap back after the use of medication.

Side effect of drug:

Allergic conjunctivitis, redness of eye and burning sensation can be experienced as side effect.

Unusual taste of mouth and drying can be seen after having medication.


  • Potential effect on respiratory and cardiac activity and Cardiac failure
  • Ocular hypersensitive patients should use the drug cautiously.
  • Myasthenia gravis patient should use drug carefully.
  • Patient suffering from COPD should be cautious while using the drug.
  • One should maintain hygiene while using the medicament and close the medicine cap tightly to maintain the sterile conditions